Polynomic

Available in 5l IU and 7.5L IU vial

Product Overview

Polymyxin B is an antibiotic that disrupts the outer cell membrane of Gram negative
bacteria, binds and neutralizes lipopolysaccharide, and inhibits respiration of
Gram-negative bacterial cells
Polymyxin B advantages
I
Polymyxin B is indicated for the treatment of
infections of the urinary tract, meninges, and blood
stream, caused by susceptible strains of
Pseudomonas aeruginosa
Contraindication
Injection should be used with caution in patients with liver
disease. Dose adjustment of Vorifun Injection may be
needed. Regular monitoring of liver function tests is advised
while you are using this medicine.
Side Effects
Safety of polymyxin B has not been established in pregnancy, breast feeding, pediatrics,
and geriatrics8. Polymyxin B should no be used in pregnancy unless the benefit
outweighs the risk8. Nursing mothers should either stop nursing or stop polymyxin B
treatment depending on the risks to both the mother and child8. Pediatric patients
should be frequently monitored for renal function and no dosing information is available
in children under 2 years of age8. Geriatric patients should have renal function assessed
before and regularly during therapy.